Cell death in Leishmania
نویسندگان
چکیده
منابع مشابه
Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes.
In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes. Miltefosine induced a process of programmed cell death, which was determined by the externalization of phosphatidylserine, the incorporation of propidium iodide, cell-cycle arrest at the sub-G0/G1 pha...
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Demonstration of features of a programmed cell death (PCD) pathway in protozoan parasites initiated a great deal of interest and debate in the field of molecular parasitology. Several of the markers typical of mammalian apoptosis have been shown in Leishmania which suggested the existence of an apoptosis like death in these organisms. However, studies to elucidate the downstream events associat...
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ژورنال
عنوان ژورنال: Parasite
سال: 2019
ISSN: 1776-1042
DOI: 10.1051/parasite/2019071